The National Mental Health Programme in the Ministry of Public Health with the support of the World Health Organization developed a Practical Guide for Media Professionals on the Coverage of Mental Health and Substance Use. The guide is designed to be used by journalists, news reporters, anchors, television shows hosts, social media bloggers, script writers and other media professionals. It is contextualized and culturally adapted to the media scene in Lebanon so as to answer questions related to mental health and substance use. The guide helps media professionals produce successful media outputs on mental health and substance use. It was prepared based on findings from interviews with media professionals which aimed to explore their needs and the challenges they face when addressing mental health and substance use topics.